Diabetic kidney disease (DKD): Not just an adult problem!

Saturday, April 26, 2025

10:00am – 11:30am HST

Location: Convention Center: 316 A

CE: 1.5

Selected By: ASPN

Chair(s)

Rhiana Lau, MD (she/her/hers)

Pediatric Nephrologist | Division Chief Pediatric Specialties | Assistant Professor
Hawaii Pacific Health | University of Hawai'i John A. Burns School of Medicine
Honolulu, Hawaii, United States
KB

Kelly Bergmann, DO, MS (he/him/his)

Pediatric Emergency Physician, Emergency Research Director
Emergency Medicine
Children's Minnesota
Minneapolis, Minnesota, United States

Disclosure(s):

Rhiana Lau, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Kelly R. Bergmann, DO, MS: I do not have any relevant financial / non-financial relationships with any proprietary interests.

This session will highlight the spectrum and burden of diabetic kidney disease (DKD) in childhood, covering both type 1 and type 2 diabetes. The session will cover a range of topics spanning epidemiology of acute kidney injury (AKI) in diabetic ketoacidosis (DKA), hyperfiltration injury, albuminuria and chronic kidney disease (CKD) progression in DKD, and the latest research on sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor (GLP-1R) agonists in the prevention and treatment of DKD progression.

Learning Objectives:

Describe the epidemiology, clinical presentation, management and long-term outcome of AKI in children with T1DM presenting in DKA.
Delineate the epidemiology and clinicopathologic features of DKD in children with T2DM and describe the long-term outcomes and psychosocial challenges identified by recent studies.
Describe the pharmacology, rationale for use, risks, benefits and outcomes of SGLT2 inhibitors and GLP-1R agonists in patients with DM.

Presentations:

10:00am – 10:30am HST

Acute Kidney Injury (AKI) Associated with Diabetic Ketoacidosis and Kidney Outcomes in Type 1 Diabetes Mellitus
Speaker: Cherry Mammen, MD (he/him/his) – University of British Columbia Faculty of Medicine
10:30am – 11:00am HST

The Spectrum of Kidney Disease in Childhood Type 2 Diabetes Mellitus (T2DM)
Speaker: Allison Dart, MD, MSc (she/her/hers) – Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba
11:00am – 11:30am HST

The Role of SGLT2 Inhibitors and GLP-1R Agonists in Treatment and Prevention of DKD: the Adrian Spitzer Lectureship
Speaker: Petter Bjornstad, MD – University of Washington School of Medicine, and Seattle Children's Hospital