Managing complex cases in nephrotic syndrome: Understanding the International Pediatric Nephrology Association (IPNA) clinical practice guidelines

Friday, April 25, 2025

5:30pm – 7:00pm HST

Location: Convention Center: 316 A

CE: 1.5

Selected By: ASPN

Chair(s)

KG

Kelly Garrity, MD (she/her/hers)

Assistant Professor of Pediatric Nephrology
Medical University of South Carolina
Charleston , South Carolina, United States
Zubin Modi, MD, MS (he/him/his)

Assistant Professor
Pediatrics / Division of Pediatric Nephrology
University of Michigan Medical School
Ann Arbor, Michigan, United States

Disclosure(s):

Kelly Garrity, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Zubin J. Modi, MD, MS: Boehringer Ingelheim (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator); Phase V (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator)

This session will explore the spectrum of challenging nephrotic syndrome (NS) cases to highlight International Pediatric Nephrology Association (IPNA) clinical practice guidelines with respect to steroid-dependent nephrotic syndrome (SDNS) and steroid-resistant nephrotic syndrome (SRNS). The session will provide an overview and epidemiology of childhood NS. Complex, difficult-to-manage SSNS and SRNS cases will be presented. Experts will discuss potential diagnostic and management approaches to these cases in the framework of recent IPNA guidelines and will highlight the relevant literature that anchored their medical decision making.

Learning Objectives:

Describe the epidemiology of steroid sensitive and steroid resistant nephrotic syndrome
Learn management approaches to a challenging case of SDNS with respect to current IPNA clinical practice guidelines and published literature
Learn management approaches to a challenging case of SRNS with respect to current IPNA clinical practice guidelines and published literature

Presentations:

5:30pm – 6:00pm HST

Overview and Epidemiology of Steroid-sensitive and Steroid-resistant Nephrotic Syndrome
Speaker: Susan M. Samuel, MD MSc FRCPC (she/her/hers) – University of British Columbia
6:00pm – 6:30pm HST

Steroid-dependent Nephrotic Syndrome: Challenging Cases
Speaker: Gabriel Cara Fuentes, MD, PhD (he/him/his) – Nationwide Children's Hospital
6:30pm – 7:00pm HST

Steroid-resistant Nephrotic Syndrome: What Are My Options?
Speaker: Marina Vivarelli, MD (she/her/hers) – Bambino Gesù Children's Hospital, Rome Italy